Efficacy and Safety of Growth Hormone (GH) Therapy in Patients with SHOX Gene Variants
Background: Among the potential indications for growth hormone (GH) therapy is the presence of mutations in the bbs-dog-collar- SHOX (short stature homeobox-containing) gene, located in the telomeric pseudotautosomal region (PAR1) on the short arm of both sex chromosomes.Despite general recommendations supporting GH therapy in these cases, there is